Cannabinoid Receptors, (which is located throughout the body), are part of the endocannabinoid system, which is involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory.
Cannabinoid receptors are of a class of cell membrane receptors in the G protein-coupled receptor superfamily. As is typical of G protein-coupled receptors, the cannabinoid receptors contain seven transmembrane spanning domains. Cannabinoid receptors are activated by three major groups of ligands: endocannabinoids, produced by the mammillary body; plant cannabinoids (such as cannabidiol, produced by the cannabis plant); and synthetic cannabinoids (such as HU-210). Scientific experts have discovered two different cannabinoid receptors that react to the presence of cannabinoids, including cannabidiol. These include Cannabinoid Receptor 1, or CB1 for short, and Cannabinoid Receptor 2, or CB2.
The CB1 receptor is expressed mainly in the brain (central nervous system or "CNS"), but also in the lungs, liver and kidneys.
They are also found in other parts of the body. For instance, in the liver, activation of the CB1 receptor is known to increase de novo lipogenesis.
The CB2 receptors are mainly expressed on T cells of the immune system, on macrophages and B cells, and in hematopoietic cells. They also have a function in keratinocytes. They are also expressed on peripheral nerve terminals. These receptors play a role in antinociception, or the relief of pain.
It is always good to understand why and how cannabidiol is beneficial to the human body and how important these substances affect the body.
(Biggie voice) I love it when you call me big papa... .
The Big Papa Lemon Lavender Libation
1.5-2 ounces of fresh lemon juice
1/4 ounce of lavender simple syrup (get the recipe on ChronVivant.com)
1/4 ounce Maraschino cherry juice (can substitute with grenadine)
2-3 dashes bitters
2-3 drops of P&B tincture
Lightly sparkling mineral water
Combine all the above ingredients (*except for mineral water*) with ice in a shaker and shake until cold.
Strain into a glass and top off with lightly sparkling mineral water.
CANNABIS x FITNESS SPOTLIGHT
🤙🏽 Wanna give a huge shout to my friend @cannabisweetie. She's the co-founder of @stigma.activewear and their mission aligns directly with ours. They "aim to uplift the negative perception of cannabis users by representing a lifestyle that supports overall wellness, productive energy and a positive mindset."
✊🏽Thank you for being a positive force in the Cannabis community and so open to new ideas & people. Also don't forget to stop by and check them out on August 4th at the San Francisco @the420games .
💯 Every Monday & Thursday morning we'll be Shining much deserved spotlights on individuals bridging the gap between Cannabis and Fitness! .
📲 Tag all of your friends and family members who are a positive force in the Cannabis x Fitness Community .
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The Health Effects of Cannabis and Cannabinoids: The Current State of Evidence and Recommendations for Research.
Therapeutic Effects of Cannabis and Cannabinoids
• In adults with chemotherapy-induced nausea and vomiting, oral cannabinoids are effective antiemetics.
• In adults with chronic pain, patients who were treated with cannabis or cannabinoids are more likely to experience a clinically significant reduction in pain symptoms.
• In adults with multiple sclerosis (MS)-related spasticity, short-term use of oral cannabinoids improves patient-reported spasticity symptoms.
• For these conditions the effects of cannabinoids are modest; for all other conditions evaluated there is inadequate information to assess their effects. “We found conclusive or substantial evidence (ranging in modest to moderate effect) for benefit from cannabis or cannabinoids for chronic pain, chemotherapy-induced nausea and vomiting, and patient-reported symptoms of spasticity associated with multiple sclerosis.” Sources:
National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Board on Population Health and Public Health Practice; Committee on the Health Effects of Marijuana: An Evidence Review and Research Agenda.
Washington (DC): National Academies Press (US); 2017 Jan 12.
Our lab reports show you exactly what our products consists of and the percentage levels by weight. Our 2500mg Full Spectrum Tincture is 100% natural whole plant extract and contains up to .3% THC (legal levels for Industrial Hemp). Although you will most likely fail a urinalysis for THC if using a Full Spectrum product, the levels of THC are not high enough to cause any “psychoactive or high effects”, so you get the potential therapeutic benefits of THC, highlighted by the entourage effect, without the high. Some common naturally occurring cannabinoids in our Full Spectrum products include 🔺9-THC, CBD, CBDV, CBG, CBC, CBDA, and CBN. Each have their own unique (potential) therapeutic effects. We will post a blog in our Team Room on Facebook highlighting the potential benefits of these various cannabinoids and common terpenes, backed by links to scientific studies because we believe references matter. The more you know with @un_canna #UnCanna#UnCannaCBD
The #Hemp Business Journal estimated that the #CBD market will grow to a $2.1 billion market in consumer sales by 2020 with $450 million of those sales coming from hemp-based sources. That's a 700% increase from 2016. In 2015, the market for consumer sales of hemp-derived CBD products was $90 million, plus another $112 million in marijuana-derived CBD products which were sold through #dispensaries – bringing a total CBD market to $202 million last year.
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